Dr Katherine Brown

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Biography

I am a post-doctoral researcher at the Virology Division in the Department of Pathology at the University of Cambridge working with Dr. Andrew Firth.

My main research focus is detecting novel and under-researched RNA viruses in non-model organisms, particularly insects and other arthropods, and characterising their evolution. I am also interested in software development for computational biology and have developed the tool CIAlign (github.com/KatyBrown/CIAlign) for cleaning and visualising multiple sequence alignments.

I have previously completed a Computational Genomics and Training (CGAT) fellowship at the University of Oxford and a PhD in endogenous retroviral evolution at the University of Nottingham.

I am currently involved in teaching Genomics on the Certificate in Genetics course.

Qualifications:

PhD, University of Nottingham

MSc, University of Edinburgh

BSc, Biology

Selected Publications

JOURNAL ARTICLES

Tumescheit C, Firth AE, Brown K. (2022). CIAlign: A highly customisable command line tool to clean, interpret and visualise multiple sequence alignments. PeerJ. 10:e12983. doi:10.7717/peerj.12983 , 2022
Khan YA, Loughran G, Steckelberg AL, Brown K … Kieft JS, Firth AE, Atkins JF (2022). Evaluating ribosomal frameshifting in CCR5 mRNA decoding. Nature. 604(7906):E16–23. doi:10.1038/s41586-022-04627-y , 2022
Echavarría-Consuegra L, Cook GM, Busnadiego I, Lefèvre C, Keep S, Brown K … Irigoyen N (2021) Manipulation of the unfolded protein response: A pharmacological strategy against coronavirus infection. PLOS Pathogens 17(6): e1009644. doi: 10.1371/journal.ppat.1009644 , 2021
Stewart H, Brown K, Dinan AM, Irigoyen N, Snijder EJ, Firth AE (2018) Transcriptional and translational landscape of equine torovirus. Journal of Virology. 92: e00589-18. doi:10.1128/JVI.00589-18 , 2018
Brown K, Tarlinton RE (2016). Is gibbon ape leukaemia virus still a threat? Mammal Review. 47: 53-61. doi:10.1111/mam.12079 , 2016
Brown K, Emes RD, Tarlinton RE (2014). Multiple groups of endogenous epsilonretroviruses conserved across primates. Journal of Virology. 88: 12464-12471. doi:10.1128/JVI.00966-14 , 2014

Institute of Continuing Education
Madingley Hall
Madingley
Cambridge
CB23 8AQ

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