Institute of Continuing Education (ICE)
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Lucy read Natural Sciences at the University of Cambridge. After graduating, she worked as a Research Assistant with Professor Richard Cornall at the University of Oxford, where she explored models of immunodeficiency. Lucy began her PhD with Professor Paul Klenerman at the University of Oxford in 2015. During her PhD, she studied a population of human innate-like T cells, known as mucosal-associated invariant T (MAIT) cells, focussing on their single-cell transcriptional profile in tissue and following activation. During her PhD, she developed skills in bioinformatics and since January 2021, has worked as a trainer for the Oxford Biomedical Data Science Training Programme alongside her research. Last year, Lucy was involved in a large multidisciplinary project characterising the immune response to COVID-19, and is currently investigating the innate immune response to COVID-19 vaccines using transcriptional approaches. The goals of this work are to identify differences in the immune response across vaccine platforms and regimens, and to identify innate immune predictors of the adaptive immune response. Lucy is an enthusiastic teacher and believes that everyone has something valuable to contribute to discussions. She is open and friendly, and aims to ensure that all of her students meet their potential.
Innate-like T cells, particularly mucosal-associated invariant T (MAIT) cells
Use of single-cell multimodal omic methods to characterise the human immune system, including tissue-specific cell populations and immune responses to vaccination
Current project: investigating the innate immune response to COVID-19 vaccines in healthy and immunosuppressed individuals
British Society of Immunology