Lectures focus on how genetic variation is created and how genes are passed from generation to generation. As well as a broad introduction to the subject, the course aims to promote discussion about the current and future application of the human genome project, genomic data and genomic editing in the medical field. Students also gain experience in lab work, data interpretation and presentation and the course includes visits to local research institutions to learn more about the practical side of research.
Watch a short video featuring tutor Dr Maya Ghoussaini.
What will I be studying?
The course is taught through three termly units, each having its own topic. The Saturday day-schools take place in Cambridge, with the first taking place at Madingley Hall, the headquarters of the Institute of Continuing Education, on 7 October 2017 and the remaining sessions at the Science Education Centre, the Pharmacology Department and the Strangeways Research Laboratory.
The course guide, giving information about course-content, objectives, assessment and teaching venues, is given below.
Unit 1: DNA, the stuff our genes are made of
Teaching will take place on 5 Saturday day-schools: 7 October, 21 October, 4 November, 11 November and 25 November 2017
This unit aims to introduce the core concepts of what genes are and how they work, enabling students to appreciate the transfer of information from DNA to living cells. Practical work in the laboratory will allow students to observe cell structure and to appreciate how DNA can be handled and manipulated in the laboratory.
Unit 2: From genes to genomes
Teaching will take place on 4 Saturday day-schools: 20 January, 27 January, 3 February and 17 February 2018
The second unit explores some of the many areas of active whole genome research which followed on from the Human Genome Project and led to an unprecedented transformation in our understanding of human diseases and medical practices. We explain how genetic variation across the human genome can be used to study susceptibility to diseases and the role of epigenetics in gene expression and disease. We focus particularly on cancer and explain how we are currently using genome editing technologies to edit the genome of cells grown in the lab, in the hope of curing hereditary diseases in the future.
A fieldtrip will take place around the end of Unit 2 or early in Unit 3: date to be confirmed.
Unit 3: Genetics: past, present and future
Teaching will take place on 5 Saturday day-schools: 21 April, 5 May, 12 May, 26 May and 2 June 2018
This unit introduces the theory of evolution and the science behind the inheritance of specific characteristics, by considering how genes are passed on from generation to generation. It also discusses the potential of genetic manipulation and examine the benefits and dangers of manipulating the human genome and human reproductive processes through gene therapy.